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AC, articular chondrocytes

The primary endpoint was time to first acute exacerbation, with secondary endpoints including acute exacerbation frequency, sputum and serum NSP activity levels, quality of life scores, and safety indicators

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In patients with elevated concentration of chylomicron triglycerides and VLDL triglycerides (polygenic chylomicronaemia), diet is very important, although more difficult to implement, as it should be targeted at reduction of chylomicron synthesis in the intestinal epithelium, so fat intake must be very limited ( 2.3 mmol/l (200 mg/dl), treatment is always initiated with a statin (atorvastatin or rosuvastatin)